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DURABLE

DURABLE


Delivering a Unified Research Alliance of Biomedical and public health Laboratories against Epidemics

Delivering a Unified Research Alliance of Biomedical and public health Laboratories against Epidemics

DURABLE in figures

Duration 4 years

2023 – 2027

Budget 30M

25M funded by the European Union

19 Partners &
2 Affiliated Entity

in 15 EU Countries

170 Experts

48 Tasks

11 distributed in WPs

10 Specific Objectives

17 Milestones

29 Deliverables

DURABLE in figures

Duration

4 years 2023 – 2027

Budget 30M

25M funded by the European Union

19 Partners & 2 Affiliated Entity

in 15 EU Countries

220 Experts

48 Tasks

11 distributed in WPs

10 Specific Objectives

17 Milestones

29 Deliverables

Durable coordinator
Dr. Jean-Claude Manuguerra | Institut Pasteur, FR

“Our network DURABLE represents an important step in improving Europe preparedness and readiness to pandemic and other large-scale health threats”

About the project

Project period: 1/2/2023 – 31/1/2027
Outbreaks of infectious diseases are increasing due to multiple local and global interaction changes disrupting the fragile balance of the complex human-animal-environment ecosystem. The increased frequency and complexity of health threats require a different, unified form of preparedness and a coordinated, fast, reliable and effective emergency response.

Outbreaks of infectious diseases are increasing due to multiple local and global interaction changes disrupting the fragile balance of the complex human-animal-environment ecosystem. The increased frequency and complexity of health threats require a different, unified form of preparedness and a coordinated, fast, reliable and effective emergency response.

DURABLE is a tailored solution to this recognised need – a strong network of world-class basic and translational research institutes and public health centres across Europe with an outstanding track record in public health support with global reach. DURABLE aims to provide high-quality scientific information in record time to support HERA’s decision-making in preparing for and responding to cross-border health threats and assessing the impact of countermeasures.

DURABLE will coordinate a global collaboration, from pathogen detection, evolutionary analysis and threat characterisation, with One Health approach, to data and information collection and sharing, for optimal threat response. DURABLE is a unique multidisciplinary consortium with complementary expertise to meet this challenge and build productive interactions with HERA and other stakeholders.

Due to their outstanding track record and experience in the field, the DURABLE consortium is competent from day one. DURABLE will develop and validate a roadmap for rapid deployment of key countermeasures, test the robustness of the network, and assess key aspects of its emergency mode when simula­ting or dealing with identified threats. Additionally, DURABLE will focus on long-term sustainability by focusing on capacity building, training the next generation of researchers and developing pandemic preparedness training modules for the network and beyond.

Project objectives

DURABLE will be a one-stop shop for diagnostics, research, preparedness and response to current and future health threats for the benefit of citizens in the EU and worldwide.

DURABLE will establish a sustainable network of laboratories and research institutes that can address the barriers of better preparedness, and provide alerts, real-time scientific data and integrated analyses to HERA.

DURABLE will develop and use both non-targeted and targeted methods for identification of known and new threats


DURABLE will coordinate, integrate, analyse and share the output for rapid and direct use in public health decision making.

DURABLE will develop targeted studies to guide further evidence gathering in response to alerts

co-coordinator
Dr. Marion Koopmans | Erasmus Medical Center, NL

“DURABLE will be uniquely positioned to support HERA in responding to future health emergencies, by providing timely scientific intelligence and by translating them into operational recommendations”


On Friday May 8 2026, the WP11 network of Durable held its latest meeting, bringing together experts from across Europe to discuss emerging zoonotic challenges, surveillance strategies, and recent research findings. A major focus of the meeting was the ongoing hantavirus outbreak linked to a cruise ship, alongside two scientific presentations on viral surveillance and genomic characterization of zoonotic infections.

The meeting opened with an update from Marion Koopmans on the current hantavirus outbreak associated with a cruise ship that had passengers disembarking across multiple countries. The situation: while hantavirus is considered a severe but not highly transmissible disease, the international spread of passengers and the long incubation period make outbreak investigation challenging. Current evidence suggests limited secondary transmission, but no indication of a large-scale epidemic. Johan Neyts added insights on potential antiviral options, noting that while some compounds may show some activity, there is currently no “magic bullet.” Combination therapies and further research remain important. 

The first scientific presentation was delivered by Nathalie Worp from The Department of Viroscience of the Erasmus MC, The Netherlands, who presented her work on the worldwide diversity of hepatitis A & E viruses found in urban wastewater. In 2016, the Global Sewage Surveillance Project was initiated with the aim to explore the potential of metagenomic sequencing for monitoring viruses. Using capture-based metagenomic sequencing of wastewater samples from 62 cities across 48 countries, she demonstrated how wastewater surveillance can reveal both expected and unexpected patterns of virus circulation beyond what is visible through clinical surveillance alone. Her work highlights the value of wastewater-based surveillance for identifying zoonotic transmission pathways and improving early detection of emerging viral threats. 

The second presentation was given by Daniel Sobral from INSA, Portugal, who shared preliminary findings on the genomic characterization of an ORF virus infection in Portugal. The study highlighted the likely underrecognition of occupational zoonotic infections such as ORF virus and underscores the need for stronger collaboration between human and veterinary health sectors. 

The session concluded with a call for continued vigilance regarding hantavirus developments and a reminder for partners to share ideas for future presentations. The meeting once again demonstrated the strength of the DURABLE network in connecting expertise across disciplines and countries to better understand and respond to emerging infectious disease threats.